Experts weigh in on the best supplementals to help to break down protein, fats, and carbohydrates into simpler compounds that ...

Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

New research reveals that the enzyme HDAC5 plays a critical role in suppressing a gene (Scn4b) that regulates brain activity associated with drug-related memories, which are central to relapse in ...

Previous studies have shown that severe variants exhibit lower GCase activity levels and demonstrate a more significant decline over time during follow-up (3, 4). The diagnostic accuracy of the 4-MUG ...

We selected 65 compounds for screening via differential scanning fluorimetry (DSF) and enzyme activity assays. Interestingly, none of the selected ligands appeared as hits and the docking parameters ...

They determined the crystal structures of two such enzymes, conducted in vitro enzyme activity assays, and a thorough structure-guided mutagenesis campaign to interrogate the role of specific residues ...

This useful manuscript reports on the crystal structures of two glycosaminoglycan (GAG) lyases from the PL35 family, along with in vitro enzyme activity assays and comprehensive structure-guided ...

Key Laboratory of Analytical Science for Food Safety and Biology (MOE & Fujian Province), Department of Chemistry, Fuzhou University, Fuzhou 350108, People’s Republic of China ...