The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are ...

Figure 2: Macrophage ER stress in inflammation and apoptosis. It will be fascinating to explore whether specific lipid species are involved in engaging, negatively or positively, ER stress ...

Drug-induced liver injury (DILI) is a significant concern in clinical practice, arising from medications, herbs, and dietary ...

Beyond IBD, the study explores the emerging role of UPR in colorectal cancer. While ER stress can drive apoptosis, it can also support tumor progression by enabling cancer cells to survive in ...

Furthermore, UDCA reduces inflammation by modulating immune responses and suppressing pro-inflammatory pathways, thus ...