Published reports on placebo-controlled clinical trials and other studies investigating the use of pure opioid antagonists for the prevention and treatment of opioid-induced pruritus (OIP ...

which would expand the market for the drug significantly. They are also running mid-stage studies in other diseases associated with pruritus, including liver disease primary biliary cholangitis ...

Kapruvia was approved by the MHRA just over a year ago, becoming the first drug specifically approved for CKD-related pruritus. It adds to various therapies used to treat the condition ...

The short duration of activity of naloxone when the drug is administered as an i.v ... an opioid (fentanyl or morphine), the frequency of pruritus was decreased, with no reversal of analgesia ...