Background Aortic stenosis is a degenerative condition with high mortality in its severe stages and no preventive treatment.

which causes aortic valve fibrosis and calcification (sclerosis) and eventually hemodynamic obstruction (stenosis). Genetic studies have found CAVD to be associated with vitamin D receptor gene ...

All compounds are either investigational or being studied for (a) new use(s). Efficacy and safety have not been established. There is no guarantee that they will become commercially available for the ...

Severe aortic stenosis (AS) is the most common degenerative heart valve disease and poses a substantial burden in the elderly.1 2 In the management of cardiogenic shock (CS) secondary to AS, ...

Fibroid degeneration occurs when a uterine fibroid outgrows its limited blood supply and begins to die. Fibroids are benign uterine growths made of smooth muscle cells and fibrous tissue. Some people ...

1 Department of Cardiology, The First Affiliated Hospital of Ningbo University, Ningbo, China 2 Department of Cardiology, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China ...

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Valvular aortic stenosis is typically due to degenerative calcification, postinflammatory fibrocalcific disease (i.e., rheumatic heart disease), or a congenitally bicuspid valve. Calcification is ...

random allocation for decompression with fusion or decompression alone in a cohort of 222 patients (mean age, 66.2 years) with degenerative spondylolisthesis and spinal stenosis who underwent ...

Spinal stenosis is a narrowing of the spinal canal that causes compression of the spinal cord and/or nerve roots. Resulting pain and numbness (in the hands, arms, legs, and/or feet) can vary depending ...

Aortic valve calcification (AVC) has been shown to be a powerful assessment of aortic stenosis (AS) severity and a predictor of adverse outcomes. However, its accuracy in patients with low-flow AS has ...