Neuroscience News24d
Genetic Mutation Linked to Schizophrenia Alters Brain Function
The mutation led to higher levels of glycine decarboxylase (GLDC), an enzyme that degrades glycine, reducing NMDA receptor activation. Mice with extra copies of the GLDC gene exhibited ...
Medical Xpress28d
Mutation increases enzyme in mouse brains linked to schizophrenia behaviors
Their paper is published in Molecular Psychiatry. The mutation increases levels of glycine decarboxylase, or GLDC, an enzyme responsible for regulating glycine in the brain. Glycine activates ...
C&EN1mon
De Novo Synthesis of Tyramine in Engineered Escherichia coli Using Two-Stage Dissolved Oxygen-Controlled Fermentation
College of Biotechnology, Tianjin University of Science & Technology, Tianjin 300457, P. R. China Key Laboratory of Industrial Fermentation Microbiology of the Ministry of Education, Tianjin ...
Frontiers1y
Adeno-associated virus-mediated gene transfer of arginine decarboxylase to the central nervous system prevents opioid analgesic tolerance
In the present study, we evaluated the development of opioid analgesic tolerance in ICR-CD1 mice pre-treated with either vehicle control or intrathecally delivered adeno-associated viral vectors (AAV) ...
Frontiers3y
Thyroid Function and Low Free Triiodothyronine in Chinese Patients With Autoimmune Encephalitis
Background and Objectives: Low free triiodothyronine (FT3) is usually associated with worse functional outcome in critical illness; however, the information on thyroid dysfunction and autoimmune ...