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Chunks of flipped DNA appear to accelerate evolution in fish. This discovery could reshape our understanding of how ...
Researchers discovered that HSV-1 (herpes simplex virus) actively reshapes the 3D layout of human DNA within hours of ...
“PDI is like a double agent,” Dr Shadfar explains. “In healthy cells, it repairs DNA and helps prevent disease. But in cancer ...
Tiny, newly formed tumors shed small fragments of DNA that are swept into the bloodstream. Future cancer screening tests could detect them early.
A remarkable scientific discovery is reshaping our understanding of human evolution. The analysis of an incredibly preserved ...
Disrupting the G-loop cycle causes transcriptome dysregulation and genome instability, revealing key role in cell survival and homeostasis.
Can you briefly explain the concept of replication stress and its role in DNA repair? Liu: It's a really complicated topic. In really broad terms, replication stress is when the process of DNA ...
A homemade cake is always something to behold, but nothing quite beats a grocery store sheet cake. From the charming design details to the classic rectangular shape, it delivers a dose of nostalgia ...
MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...
In this isothermal system, we were able to drive exponential DNA replication with Taq polymerase ... on the front and 1mm thick on the back), sandwiching a 0.25mm thin Teflon sheet that defined the ...
A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind ...
The findings visualize for the first time a molecular complex -- called CTF18-RFC in humans and Ctf18-RFC in yeast -- that loads a 'clamp' onto DNA to keep parts of the replication machinery from ...