Australian cancer researchers are the first to establish a next-generation gene-editing tool for modeling and interrogating human disease.

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...