You may have heard of the fantastic-sounding "dark side of the genome." This poorly studied fraction of DNA, known as ...

This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

Bioluminescent luciferase enzymes have historically been too dim to use as probes in living tissue. But recent advances have ...

Transgenic animals continue to play an essential role in many aspects of zebrafish research, including the development of disease models. The most widely used system for zebrafish transgenesis is the ...

For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event ...

Fintel reports that on March 17, 2025, Leerink Partners initiated coverage of Nurix Therapeutics (NasdaqGM:NRIX) with a ...

Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430034, China Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical ...

In this study, we unveil a common mechanism underlying these observations for the DNA-scaffolded enzymes that acts on enzymes independent of their catalytic mechanisms. By testing a variety of ...

In this study, we show that the SUMO E3 ligase Ema2 is required for the accumulation of lncRNAs from the somatic genome and thus for TDSD and completing DNA elimination to make viable sexual progeny.

By further protein engineering and process engineering, a supreme enzyme named HotJa Phi29 DNA Polymerase was developed and showed significantly better coverage (99.75%) at a higher temperature (40°C) ...