Once scientists have zeroed in on a specific segment of DNA, how do they produce enough copies of that segment for their research? In most cases, the polymerase chain reaction, or PCR, is their ...

Arthur Kornberg compared DNA to a tape recording of instructions that can be copied over and over. How do cells make these near-perfect copies, and does the process ever vary? In reality ...

Determining the number of copies of a double stranded DNA template (be it genomic DNA, plasmid or an amplified fragment) is essential for many genetic quantification applications in research and ...

Ribosomal DNA (rDNA) is present in hundreds of copies in the genome, but has not previously been part of genetic analyses. A new study of 500,000 individuals indicates that people who have more ...

Cornell researchers found that genetic variation in AMY1, a starch-digesting gene, alters oral bacteria composition, ...

Low copy number PCR 5 Low copy number PCR amplifies low amounts of DNA (typically <100-200pg). Increasing the number of amplification cycles to 34 instead of 28 helps increase sensitivity. Additional ...

Published in Cell Genomics, the research explored how the copy number variation, or CNV, of certain DNA segments can influence cognitive abilities. Analyzing the CNV of nearly 260,000 people in ...