The revolving door of leadership at the Social Security Administration highlights growing tensions over who can access ...

GENIUS IDEA! UNIQUE & CLAMP ...

KTM has unveiled the 2026 450 Rally Replica, a near-exact replica of its Dakar Rally race bike. Built for extreme rally ...

Explore how abnormal sperm DNA impacts IVF pregnancies, increasing risks like preeclampsia and preterm birth, and learn about potential treatments. Abnormal sperm increases the risk of pregnancy ...

Lori Passmore’s group, in the LMB’s Structural Studies Division, previously identified that the FANCD2-FANCI (D2-I) protein complex acts as a DNA clamp, which closes onto DNA to initiate DNA repair at ...

We independently review everything we recommend. We may make money from the links on our site. Learn more› By Lauren Sullivan Lauren Sullivan is an editor at Wirecutter. She loves any smart tip ...

The DNA sliding clamp proliferating cell nuclear antigen (PCNA) is an essential co-factor for many eukaryotic DNA metabolic enzymes. PCNA is loaded around DNA by the ATP-dependent clamp loader ...

Clamp loaders place circular sliding clamp proteins onto DNA so that clamp-binding partner proteins can synthesize, scan, and repair the genome. DNA with nicks or small single-stranded gaps are common ...

DNA molecules supply the basic instructions that ... They built a model of rods, clamps, and sheet-metal cutouts (representing the various known pieces of the jigsaw puzzle), and evaluated it ...

The image depicts how the 911 clamp is loaded onto DNA. Credit: Courtesy of Dr. Huilin Li, Van Andel Institute Researchers revealed the 911 DNA checkpoint clamp’s role in repairing DNA damage during ...

Now, scientists at Van Andel Institute and The Rockefeller University have for the first time revealed how a key piece of this repair process - appropriately called the 911 DNA checkpoint clamp ...