Additionally, the percentage of cells with UNG2 foci also increased upon treatment with hydroxyurea (HU), a ribonucleotide reductase inhibitor that alters nucleotide pools, but not gemcitabine, a ...

With just five movies, Ryan Coogler has already established himself as one of the most talented and influential filmmakers of his generation. The fact that he is so young – he has yet to turn 40 ...

Here are the different types of data: In DNA, the As (Adenine), Ts (Thymine), Gs (Guanine) and Cs (Cytosine) represent the four nucleotide bases, the building blocks of DNA. Raw 23andMe data ...

DNA has two strands. Each strand is a sequence of four chemical bases: adenine (A), cytosine (C), guanine (G), and thymine (T). The strands are anti-parallel and complementary. ‘Anti-parallel ...

Armed with $68 million in Series B funding, Epicrispr Biotechnologies (Epic) is initiating human trials of its lead candidate EPI-321, an epigenetic therapy for the neuromuscular disorder ...

In DNA, the As (Adenine), Ts (Thymine), Gs (Guanine) and Cs (Cytosine) represent the four nucleotide bases, the building blocks of DNA. To request a raw data download, users must confirm their ...

This manuscript reports important findings that the methyltransferase METTL3 is involved in the repair of abasic sites and uracil in DNA, mediating resistance to floxuridine-driven cytotoxicity. The ...

Results We defined three patient clusters by mutational signatures independent of histomorphology. Cluster 1 (C1) was defined by spontaneous deamination of DNA 5-methylcytosine and defective mismatch ...