The official results of the BRACELET-01 (PrECOG 0113) trial have been published in Clinical Cancer Research, detailing the ...

Influence of Epithelial-Mesenchymal Transition on Risk of Relapse and Outcome to Eribulin or Cyclin-Dependent Kinase Inhibitors in ... Clinical Utility of a Circulating Tumor Cell–Based Cerebrospinal ...

The official results of the BRACELET-01 (PrECOG 0113) trial have been published in Clinical Cancer Research, detailing the safety and efficacy of ...

The cell cycle is regulated by cyclins, a type of protein that binds and activates cyclin dependent kinases ... Key kinase involved in cell division linked to abnormal blood vessel growth in ...

Cyclin-Dependent Kinase 2 Inhibitors in Cancer Therapy: An Update. Journal of Medicinal Chemistry 2019, 62 (9) ... Effect of cell cycle arrest on intermediate metabolism in the marine diatom ...

Background: The cyclin-dependent kinase (CDK)-RB-E2F axis forms the core transcriptional machinery driving cell cycle progression. Alterations in RB1 or other key components occur in many cancers, ...

In progressive fibrotic diseases, which can occur in nearly all organs, myofibroblasts are activated to differentiate into proliferating fibroblastic cells that express genes that lead to deposition ...

Programmed cell death serves as a critical defense mechanism during viral infection. The kinases RIPK1 and RIPK3, central ...