Mechanistically, ENPP1 degrades cellular cyclic GMP-AMP (cGAMP), thereby blocking activation of the STING pathway and suppressing anti-tumor immune activity in the tumor microenvironment.

Lead optimization is the process by which a drug candidate is designed after an initial lead compound is identified. The process involves iterative rounds of synthesis and characterisation of a ...

Cyclic GMP-AMP synthase (cGAS) is an essential adaptor protein required for the inflammatory response to cytosolic DNA. dsDNA activates cGAS to generate cGAMP and activate STING and the expression of ...

The cyclic GMP-AMP synthase (cGAS)/stimulator of interferon genes (STING) pathway are crucial elements of the type I interferon (type I IFN) response. cGAS senses both exogenous and endogenous DNA ...

Belrise Industries IPO GMP today and analysts signal a share listing. Belrise Industries shares are showing a bullish trend in the unlisted market, with a positive grey market premium (GMP).

Belrise Industries IPO is commanding a decent demand in the unlisted market, with a positive grey market premium (GMP). According to stock market observers, Belrise Industries IPO GMP today is ...

Belrise Industries initial public offer (IPO) got fully subscribed at 1.84 times on the second day of issue on Thursday. The Rs 2,150-crore initial share sale of automotive components maker ...

Also read: Belrise Industries and Borana Weaves - What the GMP tells about both public issues Shares of the company will be listed on both NSE and BSE on Wednesday, 28th May, 2025. Disclaimer ...

Shares of Belrise Industries are scheduled to make their Dalal Street debut on Wednesday, May 28 as the auto ancillary player is likely to deliver a premium listing for the issue, if one goes by ...

“No matter where I go, someone has an Amp story,” Stewart said. “Amp gave me this. Amp showed me this; you know Amp taught me this.” The list of artists Fiddler worked with and influenced ...

The grey market premium (GMP) of Schloss Bangalore saw a correction, given the muted bidding response for the issue. The company was last seen commanding a premium of Rs 14 per share in the ...