Harvard Medical School scientists have identified a key protein in the human immune system that drives inflammatory and ...

DelveInsight's "EMPAVELI Market Size, Forecast, and Market Insight Report" highlights the details around EMPAVELI, a complement inhibitor indicated to treat adult patients with PNH. The report ...

EMPAVELI's unique mechanism of targeting C3 broadens its applicability beyond PNH, including other complement-driven diseases like geographic atrophy and immune complex-mediated diseases. With ...

The complement cascade is a biochemical process in the blood that helps or 'complements' cells of the immune system to eliminate invading pathogens. When activated by one of three pathways ...

ARO-C3 showed a maximum mean C3 reduction of 89% and sustained reduction over 87% through 24 weeks in a Phase 1/2 study. The therapy reduced proteinuria, with a mean UPCR drop of 41% and a maximum ...

PORTLAND, Ore. (KOIN) — As soon as a potential lead came in a decades-old cold case of a missing Portland family, it was the talk of town in Cascade Locks Thursday morning. Buzz starting going ...

Through integrative omics analysis, we showed the capability of glycoproteomics as a complement to proteomics or metabolomics, to provide additional insights into the pathogenesis of (pre)diabetes. We ...

ANX005 in Guillain-Barré Syndrome (GBS): First-in-kind monoclonal antibody designed to block C1q, the initiating molecule of the classical complement cascade, with a single infusion to halt ...

Results: Comparative proteomic analysis showed that the extracellular matrix (ECM) and complement cascade signaling were predominant in scar tissues. COL11A1 and CD248 significantly contributed to the ...