Reactions analogous to flavin oxygenation have been proposed for enzymes catalyzing the cofactor-independent oxygenation of, for example, urate, 3-hydroxy-4-(1H)quinolones, p-hydroquinone ...

Notably, the engineered enzyme did not require any cofactors for conversion, unlike other oxidases, and produced vanillin on a gram scale per liter of reaction solution, with a higher catalytic ...

The team specifically proposed strategies such as introducing heterologous enzyme reactions derived from other organisms and exchanging cofactors used by microbes to expand metabolic pathways.

Fosdenopterin/rcPMP considerably improves the chances of survival and developmental progress in infants with molybdenum cofactor deficiency (MoCD type A), a rare and life-threatening genetic condition ...

The Stull lab primarily focuses on the class of enzymes that use riboflavin-derived cofactors (flavin-dependent enzymes), which catalyze a wide array of chemical transformations that are crucial for ...

Researchers have discovered that an enzyme can serve as an ideal target ... burgdorferi does not use thiamin as a cofactor and instead relies on lactate dehydrogenase (BbLDH) to convert pyruvate ...

Researchers have discovered that an enzyme can serve as an ideal target ... burgdorferi does not use thiamin as a cofactor and instead relies on lactate dehydrogenase (BbLDH) to convert pyruvate ...

The findings further support the idea that these pathogens can be a cofactor in complex neurological illnesses. Improved methods for detecting Bartonella infection in animals and humans have led ...

burgdorferi does not rely on thiamin, an essential cofactor for most organisms. Instead, it depends on the enzyme lactate dehydrogenase (BbLDH) to convert pyruvate to lactate, a process crucial ...