Hot spots can be detected by statistical analysis of genetic variation ... Figure 2: High-resolution sex-specific maps of a mouse chromosome segment. The drawback of all large-scale, high ...

For technical reasons, the English full text will be published approximately two weeks after the German print edition has been published.

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

The Igκ locus, located on chromosome 12, encompasses 24 Vκ genes, 5 Jκ genes, and 1 Cκ gene, while the Igλ locus on chromosome 17 includes 71 Vλ genes ... obtained from the NCBI database through the ...

1 observed that chromosome 17 (refs. 2 and 3) occasionally bore satellites. In 1,303 karyotype analyses from 148 different individuals, only eight of the cells had such a chromosome. It had a ...

Researchers at the Crick have uncovered which genes on the Y chromosome regulate the development of sperm and impact ...

Scientists at deCODE genetics/Amgen have constructed a complete map of how human DNA is mixed as it is passed down during ...

Systematic identification of Y-chromosome gene functions in mouse spermatogenesis. Science , 2025; 387 (6732): 393 DOI: 10.1126/science.ads6495 Cite This Page : ...

Researchers at the Francis Crick Institute studying male mice engineered with different Y chromosome deletions have uncovered which genes on the mouse Y chromosome regulate the development of ...

Chromosomes contain hundreds to thousands of genes, which are sections of DNA located at specific points on a chromosome. The Y chromosome is an exception, only containing a few dozen genes.

The map marks a major step in the understanding of genetic diversity and its impact on health and fertility. It continues 25 years of research at deCODE genetics into how new diversity is ...