Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...

TFE3 fusion proteins are the oncogenic drivers of translocation renal cell carcinoma but their mechanism of action remains ...

Who were our earliest ancestors? The answer could lie in a special group of single-celled organisms with a cytoskeleton similar to that of complex organisms, such as animals and plants.

Siegfried Musser, PhD, and his team in the Department of Cell Biology and Genetics at the Texas A&M College of Medicine have ...

Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...

Results of a phase I/II clinical trial of CALEC, limbal epithelial cell grafts generated by an innovative and rigorously standardized manufacturing protocol, showing safety and feasibility for ...

This important study reports single-nucleus multiomics-based profiling of transcriptome and chromatin accessibility of mouse XX and XY primordial germ cells (PGCs). The main conclusions of this study, ...

In a surprising turn of events, an international team of scientists has found that lead-208 (208 Pb), the heaviest known "doubly magic" nucleus, exhibits unexpected shape characteristics that ...

Single-cell genomic whole genome amplification (WGA) is a crucial step in single-cell sequencing, yet its low amplification efficiency, incomplete and uneven genome amplification still hinder the ...

Using anatomical tract tracing and immunohistochemistry, we identified octopus cells in the contralateral cochlear nucleus (CN) as the primary source of excitatory input to the SPON. Cluster analysis ...