The present crystal structure of phenylalanine hydroxylase (PAH) provides the 3D structure of the full-length human PAH, both unbound and complexed with the tetrahydrobiopterin (BH 4) cofactor.The BH ...

A transient tyrosyl-like radical with a narrow doublet X-band EPR signal is present during catalase turnover by Mycobacterium tuberculosis catalase-peroxidase (KatG). Labeling of KatG with β-methylene ...

In view of this, we assigned transcriptional cofactor activity via physical interaction with bZIP60 to NOBIRO6/TAF12b. The single nobiro6 / taf12b mutant also showed an altered sensitivity to ...

More information: Zehui Guo et al, Peptide bridging for cofactor channeling in fusion enzyme lowers cofactor input by two orders of magnitude, Chinese Journal of Catalysis (2025). DOI: 10.1016 ...

The serine proteinase plasmin is the key fibrinolytic enzyme that dissolves blood clots and also promotes cell migration and tissue remodeling. Here, we report the 2.65 Å crystal structure of a ...

Cofactor-enhanced food allergy management requires avoidance measures, particularly the combination of food allergens and cofactors, and an emergency treatment plan that may occasionally include an ...

Left: Without the immune signaling molecule interferon gamma (IFNγ), Burkholderia thailandensis bacteria (red rods) use the protein BimA (red squares) to assemble actin (green) from the host cell to ...

This process involves the cofactor nucleolin (NCL) and its RNA recognition motifs, ... (G7141, Sigma-Aldrich), 40 µg/mL catalase (C100, Sigma-Aldrich), 35 mM MEA (30070, Sigma-Aldrich) and 10 mM ...

Cofactor Genomics announced the latest validation results for OncoPrism ®, Cofactor’s breakthrough RNA-based diagnostic approach at the RNA Society’s 30th Annual Meeting.

SAN DIEGO--(BUSINESS WIRE)--Cofactor Genomics announced the latest validation results for OncoPrism ®, Cofactor’s breakthrough RNA-based diagnostic approach at the RNA Society’s 30th Annual ...

Constructing heterogeneous cofactor-dependent multienzyme cascades could promote the stability and recyclability of enzymes and cofactors, which would benefit the economic feasibility and ...