Kylie Jenner has come under fire for allegedly treating Timothee Chalamet like a 'possession', with their relationship likened to that of a mother and son rather than a romantic couple, following ...

We find that the N-terminus of SH3KBP1 binds to dynamin-2 while the C-terminus associates with the endoplasmic reticulum through calnexin, which in turn control myonuclei dynamics and ER integrity, ...

Overall, PDIA1’s disulfide isomerase activity helps lessen misfolded proteins and maintain ER homeostasis. Similar to Erp72, Erp57 exhibits a disrupted redox state in PERKi models without changes in ...

Drug Discovery Lab, Department of Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Hong Kong SAR 999077, People’s Republic of China Department of Chemistry, National University of ...

PDI plays a central role in catalyzing the formation and rearrangement of these disulfide bonds. ERp57/PDIA3 (P30101), another member of the PDI family, supports PDI in the final stages of disulfide ...

UDP-glucose:glycoprotein glucosyltransferase (UGGT) 1 and 2 are central hubs in the chaperone network of the endoplasmic reticulum (ER), acting as gatekeepers to the early secretory pathway, yet ...

S-Palmitoylation is the only reversible post-translational lipid modification. Knowledge about the DHHC palmitoyltransferase family is still limited. Here we show that human ZDHHC6, which modifies key ...