All NSAIDs variably inhibit COX-1 and COX-2 and the mechanisms of inhibition fall into three broad categories, although there are exceptions. For example, nimesulide is a weak competitive ...

That's because most NSAIDs, like ibuprofen, are COX-1 inhibitors, which block prostaglandins that produce inflammation. However, prostaglandins also protect your stomach lining (per the National ...

The study demonstrates that cyclooxygenase 1 (COX-1) inhibitors, including aspirin, enhance immunity to cancer metastasis by ...

Cox-2 inhibitors are a newer form of prescription NSAID. As you might guess, they only affect Cox-2 enzymes and not Cox-1. Two of them -- Bextra and Vioxx -- are no longer sold because of concerns ...

The COX-2 inhibitors shot to pharmaceutical fame in December 1998 ... Five months later Vioxx (rofecoxib) followed, approved for osteoarthritis, acute pain, and dysmenorrhea.1 But the use for ...

TNF inhibitor use demonstrates no negative impact on survival among patients recently diagnosed with colorectal, lung or ...

"Very lame and imperfect theories are sufficient to suggest useful experiments which serve to correct those theories and give birth to others more perfect. These, then occasion farther experiments ...