Gene therapy for cystic fibrosis is advancing fast. Explore key biotech players, clinical progress, and its potential to ...

The researchers looked at medical records of women who were either on or off modulators who became pregnant in the last 10 ...

Alyftrek is a type of medicine called a CFTR modulator. Alyftrek is designed to help make the broken CFTR protein in people with cystic fibrosis work better. Since different genetic mutations can ...

Vertex's products are known as cystic fibrosis transmembrane conductance regulator modulators, or CFTR modulators, and they "fix" the malfunctioning protein made by the CFTR gene. Now the tricky ...

The new approval makes the regimen an option for around 4,000 patients in the EU who have at least one non-class I CFTR mutation.

Vertex Pharmaceuticals VRTX announced that the European Commission (EC) has expanded the label of its blockbuster cystic ...

Vertex Pharmaceuticals (Nasdaq: VRTX) today announced that the European Commission has granted regulatory approval for a label expansion of KAFTRIO® (ivacaftor/tezacaftor/elexacaftor) in a combination ...

The approval of Alyftrek, our fifth CFTR modulator regimen, represents another significant milestone in that journey for people with CF in the UK,” said Carmen Bozic, M.D., executive vice president, ...

Sionna is also developing a portfolio of complementary CFTR modulators that are designed to work synergistically with its NBD1 stabilizers to improve CFTR function. For more information about ...

DENVER - A recent retrospective study published in CHEST(Opens in a new window) evaluated the effects of cystic fibrosis transmembrane conductance regulator (CFTR) modulator use on pregnancy ...