Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

In his work on binomial nomenclature ... which estimates how long ago two species diverged by comparing their DNA sequences. Basically in the molecular clock approach, we assume that DNA sequences ...

In this paper, we present a novel strategy to annotate full TCR sequence repertoires with their epitope specificities. The strategy is based on a machine learning algorithm to learn the TCR patterns ...