Ferroptosis plays an essential role in chronic liver diseases, and cyclooxygenase-2 (COX-2) affects liver fibrosis through multiple mechanisms. + ...

SGLT2 inhibitors are medications designed to help manage blood sugar in people living with type 2 diabetes. Learn more about the different types, as well as the benefits and side effects.

A NEW study reveals that inhibitors of cyclooxygenase 1 (COX-1), including the common drug aspirin, could enhance immune responses to cancer metastasis, offering hope for preventing recurrence in ...

Because of these roles, drugs that inhibit COX-1 can cause unwanted side effects. COX-2 inhibitors are a type of NSAID that selectively blocks the COX-2 enzyme and not the COX-1 enzyme. The goal of ...

A surprisingly large amount of non-aspirin nonsteroidal anti-inflammatory ... The release of the selective cyclooxygenase-2 inhibitors ('coxibs") and the recognition that these drugs may increase ...

Patients with spontaneous coronary artery dissection (SCAD) who are discharged on oral anticoagulation (OAC) or dual antiplatelet therapy (DAPT) that combines aspirin plus ticagrelor have a higher ...

Aspirin was introduced into clinical medicine ... At the same time, there was sufficient evidence to suggest a link between COX inhibition and adverse gastrointestinal and renal effects.

A drug developer's dream, rationally designed to quell inflammation, COX-2 inhibitors are also prime candidates for preventing cancer or its recurrence. Gary J. Kelloff, chief of the chemoprevention ...

Despite the paucity of data for COX-2 inhibitors and investigated agents, including aspirin, minocycline, and statins, with purported pleiotropic anti-inflammatory mechanisms, further research is ...