In the revised version, the authors now make this more clear. (3) Figure 5: This figure shows disruption of PP2A-B56 at the kinetochores. However, is this specific to the kinetochores? Since Vif has ...
Cell-cycle progression is highly regulated by protein phosphorylation events and involves the phosphatases CDC25, CDC14, PP1 and PP2A. The roles of PP1, PP2A and PP2Cγ and PP2Cδ in pre-mRNA ...
Inactivation of the tumor-suppressor protein phosphatase 2A (PP2A) is frequent in AML patients, making it a promising target for therapy. There are several PP2A inactivating mechanisms reported in ...
Here we identify PP2A as a phosphatase responsible for dephosphorylating the 14-3-3 binding sites in class IIa HDACs. Interestingly, dephosphorylation of class IIa HDACs by PP2A is prevented by ...