Chronic kidney disease-associated pruritus (CKD-aP) is a common comorbidity in uremic patients, particularly among those undergoing hemodialysis, with prevalence rates ranging from 10 to 77%. This ...

with the aim of achieving best-in-disease efficacy for the treatment of chronic pruritus and atopic dermatitis. The funds will also enable focused expansion of Attovia’s pipeline of multi-specific ...

It is approved for the treatment of cholestatic pruritus in patients with Alagille syndrome (ALGS) in the U.S. three months of age and older and in Europe for patients two months of age and older.

1 Specifically, maralixibat is approved—now in oral solution and tablet formulations—to treat cholestatic pruritus among ALGS patients aged 3 months and older and for cholestatic pruritus treatment in ...

Brachioradial pruritus is a neuropathic disorder that causes itching or a burning sensation on the arms and upper torso. 1,2 Repeated scratching can lead to excoriations and other types of skin ...

Faster and deeper itch relief than anti-IL-4/13 agents4--- onset of anti-pruritus effect as early as Week 2 (SM17) vs Week 4~6 (other agents), over 90% of patients achieved NRS-4 (SM17) vs 30~40% of ...

Upadacitinib outperformed dupilumab for clinically meaningful pruritus improvement among patients with moderate to severe atopic dermatitis as early as day 2 of treatment. As pruritus is the chief ...

The most common adverse events (AEs) seen in at least 20% of patients given the combination were fatigue, diarrhea, pruritus, abdominal pain, musculoskeletal pain, and nausea. The most common AEs seen ...