A summary of preclinical evaluation methods for neuroendovascular devices, including in vitro techniques, 3D-printed vascular models, in silico simulations, and in vivo models.

A Madison-based startup is working on a new approach to drug development that could reduce or replace the need for animal ...

From depressed polar bears to charismatic pandas, conservationists have used anthropomorphism, or the practice of attributing ...

Animals, from worms and sponges to jellyfish and whales, contain anywhere from a few thousand to tens of trillions of nearly ...

“Obviously, animals as that source is sort of an ... Because they were identical, Richard’s immune system thought the new organ was its own, which prevented it from rejecting the foreign ...

There were more than 48,000 organ transplants in the United States last year. They’re commonplace now, but the practice was considered experimental only a half-century ago.

Three-organ system with intestine ... Conventional preclinical models, including animal studies, do not provide sufficient information on the drug exposure of the mother and the unborn child.

MPS, such as organs-on-chips, represent a significant advancement in drug development by recreating key aspects of human biology in ways that traditional cell cultures and animal models cannot. These ...

The idea of xenotransplants—operations to transplant organs from other animals into humans—has ... in large part because the host’s immune system rejected the other species’ organ.