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C&EN21d
Activity, Reduced Toxicity, and Scale-Up Synthesis of Amphotericin B-Conjugated Polysaccharide | Biomacromolecules - ACS Publications
Amphotericin B (AMB) arabinogalactan (AG) conjugate was synthesized by the conjugation of AMB to oxidized AG by reductive amination. The conjugate was evaluated for in vitro antifungal activity and in ...
C&EN27d
Raman Imaging of an Amphotericin B Potentiator in Single-Cell Saccharomyces cerevisiae | The Journal of Physical Chemistry B - ACS Publications
Nectriatide, a fungal cyclotetrapeptide, was previously found to enhance the antifungal activity of amphotericin B (AmB), with nectriatide linear derivatives (NLDs) exhibiting even stronger ...
BioSpace27d
NextCure and LigaChemBio to Present Trial in Progress Poster for LNCB74, a B7-H4 Targeted Antibody-Drug Conjugate, as Monotherapy in Participants with Advanced Solid Tumors at ...
BELTSVILLE, Md., May 29, 2025 (GLOBE NEWSWIRE) -- NextCure, Inc. (Nasdaq: NXTC), a clinical-stage biopharmaceutical company committed to discovering and developing novel, first-in-class and ...
Morningstar27d
NextCure and LigaChemBio to Present Trial in Progress Poster for LNCB74, a B7-H4 Targeted Antibody-Drug Conjugate, as Monotherapy in Participants with Advanced ... - Morningstar
NextCure and LigaChemBio to Present Trial in Progress Poster for LNCB74, a B7-H4 Targeted Antibody-Drug Conjugate, as Monotherapy in Participants with Advanced Solid Tumors at ASCO 2025 Provided ...
ascopubs.org29d
A phase 1 first-in-human study evaluating safety, pharmacokinetics, and efficacy of ABBV-291, a CD79b-targeting antibody-drug conjugate, in patients with relapsed/refractory B ...
CD79b is expressed on most major subtypes of B-NHL and is a validated target in DLBCL. ABBV-291 is an antibody-drug conjugate (ADC) comprising the anti-CD79b antibody conjugated to a potent ...