A new catalyst promotes an asymmetric radical reaction using an engineered ligand that can differentiate between very similar ...

Scientists identify enzyme SIRT2 as key trigger of memory loss and brain inflammation in Alzheimer’s breakthrough.

Blacksmith Medicines, Inc. (Blacksmith), a leading biopharma dedicated to discovering and developing therapeutics targeting metalloenzymes, today announced the company will present data on its ...

It is now possible to obtain three-dimensional, high-resolution images of enzyme activity in tissue samples or whole ...

In undertaking this unbinding procedure, students were instructed to minimize perturbation to the enzyme’s structure by exercising precision and care, so as not to destroy protein secondary structure ...

A team at UCSF and Gladstone Institutes developed new drug candidates that show great promise against the virus that causes ...

School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China State Key Laboratory of Non-Food Biomass and Enzyme Technology, Guangxi Academy of Sciences, Nanning 530007, China ...

Inside cells, two important enzymes act like small central regulatory ... that exhibit a lock-and-key fit to the DPP8/9 active site. "These new compounds inhibit DPP8/9 with high efficacy and ...

Published in the journal RSC Medicinal Chemistry, new research targets two critical enzymes involved in the production of the hormone estrogen —aromatase and steroid sulfatase—at the same time.

Once all products are released, ATP can re-enter the active site causing detachment from actin, resetting the cycle (1). The immense subtlety of structural movement inherent in allosteric motors is ...