A new study published in Communications Medicine details the discovery of rare gene variants that increase the prevalence of type 2 diabetes in multiple generations of Asian Indian people.
Introduction: Congenital hyperinsulinism (HI) is characterized by inappropriate insulin secretion from the pancreatic beta-cells which causes severe hypoglycemia. Copy number variants (CNVs) ...
Recently, there has been a growing appreciation for the existence of cellular plasticity in the adult islet. This study probes this phenomenon by exploiting the zebrafish experimental model, which has ...
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