Of particular concern is the virus’s liking for the liver. “If you look at the number of ... and compared delivery efficiencies of the GFP molecules across the brain. AAV-PHP.B showed at least 40-fold ...

A new, streamlined AAV purification process that is both universal and scalable could ease commercialization constraint.

Potent in vivo gene editing in skeletal muscle of non-human primates by a novel, ultracompact CRISPR system delivered via a single AAV vector.

Using this model, the researchers generated proteins with mutations that were predicted to lead to improved versions of GFP and a protein from adeno-associated virus (AAV), which is used to ...