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Physician's Weekly2h
Correlation between abnormal posture, screen time, physical activity, and suspected scoliosis: a cross-sectional study.
Scoliosis considerably affects adolescents' physical well-being and quality of life. Current research offers scant data concerning the correlation between abnormal posture, screen time, physical ...
Physician's Weekly2h
Decreased CO saturation during circular breathwork supports emergence of altered states of consciousness.
Altered states of consciousness (ASCs), induced e.g. during psychedelic-assisted therapy, show potential to treat prevalent mental health disorders like depression and posttraumatic stress disorder.
Physician's Weekly2h
TMEM160 inhibits KEAP1 to suppress ferroptosis and induce chemoresistance in gastric cancer.
Chemoresistance is the most significant challenge affecting the clinical efficacy of the treatment of patients with gastric cancer (GC). Here we reported that transmembrane protein 160 (TMEM160) ...
Physician's Weekly2h
Long-Term Denosumab Treatment in Adults with Juvenile Paget Disease.
Juvenile Paget disease (JPD) is a very rare disease, mainly caused by biallelic inactivating mutations in the TNFRSF11B gene that encodes osteoprotegerin. Owing to its rarity, the treatment of JPD is ...
Physician's Weekly3h
Prevalence and comorbidity of attention deficit hyperactivity disorder in Chinese school-attending students aged 6-16: a national survey.
Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder. Despite its significance, no large-scale epidemiological study assessing ADHD, and its associated ...
Physician's Weekly3h
Cost-utility analysis of olaparib assisted targeted therapy for BRCA mutation HER2-negative early breast cancer in China and in the United States.
Olaparib, an inhibitor of poly (ADP-ribose) polymerase (PARP), has demonstrated promising outcomes in treating HER2-negative early-stage breast cancer with BRCA mutations. However, a comprehensive ...
Physician's Weekly3h
Prefrontal cortex excitatory neurons show distinct response to heroin-associated cue and social stimulus after prolonged heroin abstinence in mice.
Substance use disorder (SUD) has been linked with social impairments. The social cognitive dysfunctions can further increase the risk of the development of SUD or relapse. Therefore, understanding the ...
Physician's Weekly3h
In-hospital Mortality is Lower in Brain-Injured Patients After Admission to a Neuroscience Intensive Care Unit: A Multi-Center Cohort Study.
ObjectiveTo study the impact of dedicated Neuroscience Intensive Care Units (NSU) on clinical outcomes in patients with acute brain injury.DesignRetrospective, multicenter cohort study.Setting172 ...
Physician's Weekly3h
Time-restricted feeding protects against septic liver injury by reshaping gut microbiota and metabolite 3-hydroxybutyrate.
Liver injury is an independent risk factor for multiple organ dysfunction and high mortality in patients with sepsis. However, the pathological mechanisms and therapeutic strategies for ...
Physician's Weekly3h
Evaluation of a novel elbow joint torque measurement device in healthy subjects and stroke patients: a randomized trial.
Current clinical practice lacks quantitative assessment methods for elbow joint movements. In response to existing research limitations, this study introduces the innovative elbow joint torque ...
Physician's Weekly3h
The projected economic burden and complications of revision hip and knee arthroplasties: Insights from national registry studies.
The rising volume of primary hip and knee arthroplasties has led to a parallel increase in revision surgeries, creating significant clinical and economic challenges for healthcare systems worldwide.
Physician's Weekly3h
A Chinese prospective cohort research developed and validated a risk prediction model for patients with cervical cancer.
Cervical cancer constitutes a formidable health challenge imperiling the well-being and lives of women globally, particularly in underdeveloped nations. The survival rates among patients diagnosed ...