Envision this possible future clinical scenario: a breast cancer patient and her physicians are deciding on the best possible ...

Most studies on changes in WNT/β-catenin pathway in renal cell carcinoma (RCC ... Fzd5 (Rabbit polyclonal to Frizzled 5 ab115204 Abcam), β-catenin (Recombinant Anti-beta Catenin antibody (E247) ...

Activation of beta-catenin, the primary mediator of the ubiquitous Wnt signaling pathway, alters the immune system in lasting and harmful ways, a team of Chicago-based researchers demonstrate in ...

Department of Stomatology, The Fourth Affiliated Hospital of Soochow University, Suzhou Dushu Lake Hospital, Medical Center of Soochow University, Suzhou 215123, People’s Republic of China Center of ...

Wnt signalling is an important, evolutionarily conserved signalling pathway that determines cell fate decisions and tissue patterning during embryonic development and later development. The ...

ABSTRACT: Breast cancer is one of the most commonly diagnosed cancers and one of the most significant sources of cancer mortality. Triple negative breast cancer (TNBC) is a particularly aggressive ...

proteins act as key signaling factors in beta-catenin–dependent and beta-catenin–independent Wnt pathways. While their importance for signal transmission has been genetically demonstrated in many ...

Here, we examined the destruction complex (DC), an organelle which controls Wnt signaling and whose components phase ... XLone-Axin-tdmRuby3 (above) and Human Beta-catenin GFP purchased from Addgene ( ...

The Wnt/β-catenin pathway orchestrates development of the blood-brain barrier ... Pericyte abundance was evaluated by normalizing PDGFR-β (platelet-derived growth factor receptor beta) immuno-positive ...