Enzyme fusion is a commonly used cofactor regeneration strategy, but the high usage and limited cofactor recovery restrict the sustainability of the catalytic process. Thus, there is an urgent ...

Natural hydrogen-producing enzymes are large and extremely sensitive to oxygen. This makes it difficult to use them for the applied production of green hydrogen. Researchers from the ...

The μPl enzyme is shown in green, the SAK cofactor in yellow, and the substrate-like μPl in red. The inhibitor is depicted in cyan. The view is as in (a) Figure produced with SETOR 28.

More information: Zehui Guo et al, Peptide bridging for cofactor channeling in fusion enzyme lowers cofactor input by two orders of magnitude, Chinese Journal of Catalysis (2025). DOI: 10.1016 ...

Natural hydrogen-producing enzymes are large and extremely sensitive to oxygen. This makes it difficult to use them for the applied production of ...

Before this work was done, tantalizing mechanistic parallels between ubiquitin activation and the biosynthesis of several sulphur-containing enzyme cofactors had already been noted 20,21,22 .

Discover how sugar quietly damages your liver through dangerous mechanisms. Learn about fatty liver disease, inflammation, ...

BackgroundIVD is a key enzyme in leucine catabolism, catalyzing the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA. Defects in IVD function lead ...

Learn how eating identical foods every day creates serious health risks including nutrient gaps, food sensitivities, and ...

Treatments for multiple myeloma, melanoma, NSCLC, phenylketonuria, C3 glomerulopathy and primary immune complex membranoproliferative glomerulonephritis are under review.

How ocean-derived minerals provide superior bioavailability compared to synthetic supplements for enhanced cellular ...