"Nucleoside analogs are among the most important molecules to the advancement of modern medicine," says Michael Meanwell, assistant professor in the Department of Chemistry and corresponding ...

Throughout history, many viral diseases have proven difficult to treat. However, recent research into synthetic drugs has ...

Inosine is a nucleoside that occurs naturally in transfer RNAs (tRNAs) and is essential for proper RNA translation. It is commonly found at the wobble position of anticodons, allowing for greater ...

Deoxynucleoside analogues such as 5-aza-2-deoxycytidine (depicted by Z) are converted into the triphosphate inside S-phase cells and are incorporated in place of cytosine into DNA. Ribonucleosides ...