On average, the tumour size per mouse for the no running wheel group was about 3.5 times more than in the exercise group. "In both models, voluntary running decreased the number of non-malignant ...

Objective, non-invasive means of assessing severity are scarce, which led the authors to ask whether voluntary wheel running (VWR) in mice might provide such a measure, based on previous work ...

Since wild animals eagerly use running wheels, that sort of running is a voluntary, rather than compulsive, behavior. That wheel running continued even in the absence of a tasty snack “implies ...

More information: Zoe Thompson et al, Effects of food restriction on voluntary wheel-running behavior and body mass in selectively bred High Runner lines of mice, Physiology & Behavior (2024).

One was the famous High Runner line. Back in 1993, researchers began selecting mice who showed unusually high levels of voluntary wheel running and breeding them with each other. The mice in the ...

“Body weight influences musculoskeletal adaptation to long-term voluntary wheel running during aging in female mice.” Aging increases the prevalence of sarcopenia and osteoporosis which are ...

Research in mice has shown how exercise increases levels of a chemical called brain-derived neurotrophic factor (BDNF), which bolsters the release of the “feel-good” hormone dopamine (DA).

that do not get as much food as they desire in a given day (1 Trusted Source Effects of food restriction on voluntary wheel-running behavior and body mass in selectively bred High Runner ...

To understand how exercise influences this process, researchers subjected rats to three weeks of chronic stress, with one group engaging in voluntary wheel running. Subsequently, they analyzed ...