Siderophore binding proteins play a key role ... erythromycin 12 and vancomycin 13 enter gram-negative cells via ... FhuA outer membrane receptor 15, with a Tyr and an Arg binding the three ...

This valuable manuscript investigates the localisation of nutrient receptors in bloodstream stage trypanosomes, with implications for both nutrient uptake and immune evasion. Results after direct ...

Understanding how molecules interact is central to biology: from decoding how living organisms function to uncovering disease mechanisms and developing life-saving drugs. In recent years, models like ...

Discover how bitter taste receptors in the intestines affect aging. A new study identifies specific receptors linked to metabolic changes, inflammation, and lipid metabolism. Learn how these ...

Objective: To systematically evaluate the literature to determine whether vancomycin-induced neutropenia is dose- or duration-related and provide clinicians with feasible treatment alternatives ...

Background: Vancomycin is administered as antimicrobial prophylaxis to patients undergoing cardiac surgery, an intervention that usually requires cardiopulmonary bypass (CPB). Previous studies ...

S ince 1961, there has been an ongoing cholera pandemic, with a rise in cases in 2022. Cholera, caused by the bacterium Vibrio cholerae, is known for its hallmark symptom: severe watery diarrhea, ...

Governments and employers’ representatives at the International Labour Organization (ILO) conference should agree to a new treaty to protect “gig” workers.

The concurrence of enzymatic reaction and ligand–receptor interactions is common for proteins, but rare for small molecules and has yet to be explored. Here we show that ligand–receptor interaction ...