News

Protein pivotal for B-cell cancers gets a closer look
Using a modern imaging technology known as cryo-electron microscopy, researchers at UT Southwestern Medical Center have ...
The Scientist21h
New Cholera-Toxin Binding Protein Stops Diarrhea in its Tracks
S ince 1961, there has been an ongoing cholera pandemic, with a rise in cases in 2022. Cholera, caused by the bacterium ...
News-Medical.Net2d
Electron microscopy study shows how two enzymes work in tandem to process proteins
Healthy cells are constantly breaking down proteins and building up new ones with the help of enzymes aptly named unfoldases, ...
C&EN4d
All-Atom Simulations Reveal the Intricacies of Signal Transduction upon Binding of the HLA-E Ligand to the Transmembrane Inhibitory CD94/NKG2A Receptor
(9) It is likely that the signal transduction between HLA-E and the NKG2A/CD94 receptor primarily takes place via the α2 HLA-E domain, while the majority of energetically favorable interactions are ...
C&EN6d
Site-Specific Phosphorylation of PSD-95 PDZ Domains Reveals Fine-Tuned Regulation of Protein–Protein Interactions
The postsynaptic density protein of 95 kDa (PSD-95) is a key scaffolding protein that controls signaling at synapses in the brain through interactions of its PDZ domains with the C-termini of ...