This was circumvented in 2005 when a breakthrough discovered that replacing naturally occurring uridine with derivatives ... up studies confirmed that this nucleoside modification improved mRNA ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. The PCR-amplified complementary DNA fragments were assembled ...

State Key Laboratory of Elemento-Organic Chemistry, Frontiers Science Center for New Organic Matter, Department of Chemical Biology, College of Chemistry, Nankai University, Tianjin 300071, China ...