During ubiquitination, a group of enzymes called E3 ubiquitin ligases attach a small protein called ubiquitin to other proteins. This tagging, in turn, helps determine the fate of the targeted ...

This study found that the ubiquitination that inactivates Nrf1 ... These atypical ubiquitin chains were resistant to deubiquitinating enzymes. Thus, in the absence of NGLY1, Nrf1 is detected ...

Ubiquitination, a fundamental post-translational ... The review delves into the E3 ubiquitin ligases, a specialized class of enzymes responsible for targeting specific proteins for degradation ...

Figure 5: Parkin exhibits ubiquitination activity in vitro. Parkin consists of two functionally different domains (Fig. 6): the C-terminal RING-box, which recruits a specific E2 enzyme (UbcH7 ...