Explores how inhalational anesthetics trigger general anesthesia through interaction with calcium channel RyR1.

A new study uncovers the long-elusive mechanism of inhalational anesthetics by identifying the RyR1 calcium channel as a key molecular target.

Since their effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general ...

Since their anesthetic effects were discovered approximately 180 years ago, inhalational anesthetics have been used for ...

A research team at The University of Tokyo has discovered that inhalational anesthetics activate a protein called type 1 ryanodine receptor (RyR1), ...

Musselman, M.E. and Saely, S. (2013) Diagnosis and Treatment of Drug-induced Hyperthermia. American Journal of Health-System Pharmacy, 70, 34-42. ... Clinical Strategies for Managing Anticholinergic ...

Malignant Hyperthermia is a rare but life-threatening condition, stemming from a reaction to certain medications such as succinylcholine and certain anesthetic medications. Up to 700 cases are ...

Hyperthermia, a cancer treatment using controlled heat to kill tumor cells, shows promise but faces limitations due to some ...

Since the time of the ancient Greek physician Hippocrates, cancer has been recognized as being sensitive to heat. Today, this ...

Hyperthermia, a cancer treatment using controlled heat to kill tumor cells, shows promise but faces limitations due to some ...

Malignant hyperthermia (MH): A pharmacogenetic disorder of skeletal muscle triggered by certain anaesthetic agents, leading to a hypermetabolic state and potentially fatal complications.