The spheres fall apart and release their cargo in acidic environments, such as those found inside tumors (Macromol. Rapid ...

Turning groundbreaking research from the Institut Pasteur with the support of Argobio’s start-up studio, into novel treatments for cancer, inflammatory diseases and viral infections. The platform ...

The platform leverages state-of-the-art generative artificial intelligence (AI) to design selective inhibitors of the Sec61/translocon molecular complex for blocking and degrading disease-causing ...

Further dissecting NLRC4 activation, the find that T3SS translocon components eseB, eseC and eseD are necessary for NLRC4 activation, and that delivery of purified eseB is sufficient to trigger ...

Structure of AcrH-AopB Chaperone-Translocator Complex Reveals a Role for Membrane Hairpins in Type III Secretion System Translocon Assembly.

School of Energy and Environment and State Key Laboratory of Marine Pollution, City University of Hong Kong, Kowloon, Hong Kong, China Research Centre for the Oceans and Human Health, City University ...

1 Department of Digestive Endoscopy, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China 2 Department of Gastroenterology, The First Affiliated Hospital of Jinzhou ...