We discovered the function of the thymus and made key findings on the function of the two main subsets of lymphocytes, T cells and B cells. This was the fundamental basis for modern immunology.

Interactions with self-peptide–MHC complexes on thymic epithelial cells are crucial for thymocyte survival (positive selection) and CD4 versus CD8 lineage commitment, but can also result in apoptotic ...

Longly considered as a cemetery for thymocytes, the thymus is henceforth officially recognized as the central site for self-tolerance establishment through the generation of immunocompetent and ...

MILLER 1 has shown that thymectomy in the neonatal period of life favours the development of skin benzpyrene cancer in mice.