Primary Immunodeficiency (PID) in India poses a significant health concern, with under-recognition hindering diagnosis and treatment accessibility.

[36] Gender-specific patterns in the development of autoimmune diseases ... the combined effects of the reduction in naive T cells (produced by thymus involution) in concert with an activation ...

Crown BioScience experts explore organoid models and high-content imaging to evaluate T-cell-targeted therapies and ...

For biologists, seeing is believing. But sometimes biologists have a hard time seeing. One particularly vexing challenge is ...

A team of researchers from the University of Chicago, in collaboration with researchers from the University of Pittsburgh, ...

Author for correspondence Tel.: +44 191 222 5462 steven.o'reilly@newcastle.ac.uk T cells develop in the thymus, where they undergo positive and negative selection to produce a nonself-binding T ...

“To uncover the reason for this variability in stem cell-based embryo models, you need to have measures early in the development to see what goes wrong. However, such measurements typically destroy ...

During morphogenesis—the process by which living organisms take shape—cells collectively position themselves in specific ways ...

Scientists could reshape cancer treatment by helping powerful drugs work better in the body by exploiting a surface protein called CD36 that helps pull substances into cells. This dramatically ...

Both groups benefited from therapy equally, but there were differences in their immune responses and immune cells. For example, T cells are the cells that help destroy damaged cells, bacteria or ...

Our immune systems weaken as we get older, making fewer cells that fight infection and help us recover from illness and injury. Scientists aren't completely sure why. They may have a better idea now, ...

It’s no wonder the cell and gene therapy ... and final guidance for CAGT development, including how to manage manufacturing changes for CAGTs and CAR-T-specific recommendations.