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Inhibitors of Apoptosis Proteins (IAPs) are a family of anti-apoptotic proteins that play a pivotal role in apoptosis in general but also as oncoproteins in cancer progression and, more importantly, ...
TRAF2 and TRAF2-related proteins, such as TRAF1 and cIAP1/2, are recruited to activate TNFR2. Then, TNFR2 activates NF-κ B, STAT5, YAP, and other transcription factors through different pathways to ...
Disturbance of Itch LLPS impairs the turnover of lipid droplets. We propose that the feedback regulation of ubiquitination and LLPS is a general mechanism for the modulation of HECT E3 ligases. Lipid ...
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S.W. Chung and J.S. Kim equally contributed to this article as co-first authors. W.-M. Choi and K.M. Kim equally contributed to this article as co-corresponding authors.
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