The mechanism of action involves the regulation of the TLR 9 signaling pathway. The HaCaT (Procell CL-0090) cell line was purchased from Procell Life Science & Technology Co., Ltd. HSV-2 was purchased ...

Ten years of substantial work by Université de Montréal immunologist Nathalie Labrecque's team at the Montreal Clinical ...

New research identifies the liver protein PTPRD as a key regulator of metabolic liver disease. Reduced levels of PTPRD ...

Cancer remains a leading cause of death globally, with lung cancer being particularly lethal. Despite advancements in diagnostics and therapies, the five-year survival rates for advanced tumors have ...

Researchers have found a potential new way to slow the progression of lung fibrosis and other fibrotic diseases by inhibiting the expression or function of Piezo2, a receptor that senses mechanical ...

Scientists at Pennington Biomedical Research Center have gained greater clarity in the brain regions and neurons that control metabolism, body temperature and energy use.

Autoimmune diseases are a pathophysiological state wherein immune responses are directed against, and damage, the body's own tissues (autoimmunity). Common examples of autoimmune disease include ...

Here the authors show that IFN-III promote plasmacytoid dendritic cells (pDC) activation and TLR-7 responses by counteracting immunosuppression induced by TGF-β and PGE-2.

Research on neuroprotective mechanisms aims to understand how the nervous system is protected from injury or degeneration. These studies commonly use animal ...