In living organisms, protein molecules with different chemical structures called proteoforms, are produced from a single gene ...

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy ...

A prominent research group from Ehime University and its close partner at Kiel University have published their third ...

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

Research on the development, physiology and pathophysiology of reproductive disorders is important, as evidence suggests that many adult-onset diseases can be traced back to disruptions during early ...

Taken together, epigenetic changes that alter chromatin structure have surpassed the proof of principle stage and now offer new dimensions for cancer diagnosis and therapy. With expanding use of ...

Dec. 16, 2024 — Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats. It turns out that two of these microbially-modified ...

Chemical modification describes the modification, addition or removal, through chemical reaction, of any of a variety of macromolecules, including proteins and nucleic acids. It refers to the use ...

President Trump has appointed Chris Rocheleau as the acting FAA administrator following a tragic aircraft collision near Washington, D.C. Rocheleau, with over two decades of experience at the FAA ...

Interneurons have a multipolar structure that allows them to receive multiple signals and then send a unified command to another neuron. In this way, you can think of interneurons as traffic ...