While the drug’s full mechanism isn’t known, stimulation of those serotonin receptors may drive serotonin levels in reward-related areas of the brain down. This might in turn send dopamine ...

First, because electric stimulation of the DRN can also activate neurons that don't use serotonin to communicate with each other, and second, using drugs can affect other serotonin in the brain ...

or with drugs that impair serotonin metabolism (eg, MAOIs, linezolid, IV methylene blue). Potentiates alcohol, sympathomimetics. CNS stimulation with reserpine. Potentiated by CYP2D6 inhibitors ...

Serotonin syndrome is a preventable, drug-related complication that results from increased brain-stem serotonin activity, usually precipitated by the use of one or more serotonergic drugs.

Our work ties the improvement in cognitive function to the specific 5HT 4 receptor and suggest that direct serotonin 4 receptor stimulation ... to treat patients with drugs which specifically ...

Mucosal stimulation in the gut, triggered by meals, activates tryptophan hydroxylase-1 (Tph1). Activation of this enzyme results in synthesis from tryptophan of serotonin that then diffuses into ...