In this context, we feel that ambiguities in the usage of the terms 'leader sequences' and 'signal peptides' require clarification. The translocation of secretory proteins across intracellular ...

In an initial step, SRP54 recognizes the hydrophobic N-terminal ‘signal sequences’ found on most proteins that travel through the secretory pathway as they emerge from translating ribosomes (Fig.

an expert in mitochondrial pathology and peptide therapies for neurodegenerative diseases, have validated a novel therapeutic strategy targeting both secretory dysfunction and mitochondrial defect ...