Forkhead box protein L2 (FOXL2) is a protein involved in ovary development and maintenance, among other functions. Mutations in its gene are involved in ovarian failure and granulosa cell tumors, ...

Granulosa cell tumors (GCTs) are a rare type of ovarian tumor that arise from the sex-cord stromal cells of the ovary. These tumors can be classified into two main types: adult granulosa cell ...

What factors contribute to treatment resistance in chimeric antigen receptor (CAR)-T cell therapy treatments for solid tumors? While CAR-T therapy treatments have proven effective in patients with ...

to target a cell-surface receptor called DR5 (death receptor 5) that many tumor cells have. When activated, DR5 can trigger the death of these cells by a self-destruct process called apoptosis.

Scientists have struggled for decades to understand why radiation therapy kills cells from the same tumor in different ways. This is important because some forms of cell death are unnoticed by the ...

Chimeric antigen receptor-T (CAR-T) cell therapy, initially successful in hematologic malignancies, presents a promising avenue for treating solid tumors, including CRC. This review explores the ...

We look forward to working together to optimize iPSC-derived allogeneic cell therapies that have the potential to improve patient outcomes and reshape how we treat solid tumors." ...

Brain Tumor Organoids Accurately Model Patient Response to CAR T Cell Therapy Dec. 9, 2024 — Researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM ...

Hall of Famer Dwyane Wade had surgery to remove a cancerous tumor from his right kidney in December 2023, he revealed during his podcast published on Thursday. Wade, who turned 43 on Jan. 17 ...

Hall of Famer Dwyane Wade said he had surgery on his kidney in 2023, with doctors removing a tumor that was later deemed to be cancerous. In comments made on his "The Why with Dwyane Wade" podcast ...

We look forward to working together to optimize iPSC-derived allogeneic cell therapies that have the potential to improve patient outcomes and reshape how we treat solid tumors." "Cell therapies ...