Dapirolizumab pegol, a novel CD40L inhibitor, is superior to placebo for achieving low disease activity and remission in ...

More than 40% of patients with systemic lupus erythematosus in a large international study reported insufficient levels of physical activity, with low activity levels correlated to worsening of ...

[3] In general, one would expect that illnesses mediated by CD4 + T cells -- such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) -- would occur less frequently in this setting ...

Int J Clin Rheumatol. 2012;7(5):541-558. Pregnancy may have a detrimental effect on other major organs/systems, such as the heart, CNS, lungs and pulmonary arterial system, with associated high ...

Background SLE is a complex autoimmune disease with heterogeneous manifestations and unpredictable outcomes. Early diagnosis is challenging due to non-specific symptoms, and current treatments only ...

Diagnosis of SLE in early stages is challenging due to the heterogeneous nature of presenting symptoms and the poor performance metrics of the screening ANA test. Even the more specific ...

However, its usefulness in evaluating muscle lesions in polymyositis and dermatomyositis syndromes (PM/DM) has not been established. Methods 33 patients with PM/DM who had undergone FDG PET were ...

There is currently no cure for lupus, also known as systemic lupus erythematosus (SLE), and it remains a serious illness that can harm body systems. Yet a lupus diagnosis no longer means an early ...